Cy5.5-N-羟基琥珀酰亚胺酯|CY5.5 NHS ester|金畔生物


Cy5.5-N-羟基琥珀酰亚胺酯

货号:AGF1345A
包装:1mg,5mg,25mg,50mg

  • 英文名:Cyanine5.5 NHS ester
  • 分子式:C44H46ClN3O4
  • 分子量:716.31
  • 品牌:Lumiprobe
  • 产品详情质检信息

    订购货号 产品名称及规格
    17020 Cyanine5.5 NHS ester, 1 mg
    27020 Cyanine5.5 NHS ester, 5 mg
    47020 Cyanine5.5 NHS ester, 25 mg
    57020 Cyanine5.5 NHS ester, 50 mg
    67020 Cyanine5.5 NHS ester, 100 mg
     
    Cy5.5 NHS是近红外胺类活性染料。

    CY5.5 NHS ester是用于标记多肽、蛋白和寡核苷酸的氨基基团的活性染料。CY5.5属于是近红外荧光染料,当背景荧光有干扰时适宜用它来做标记以进行荧光分析。它也可以用于活体成像实验。该染料可以替代Alexa Fluor 680和DyLight 680。

    Cy5.5-N-羟基琥珀酰亚胺酯|CY5.5 NHS ester|金畔生物

    推荐手册:
    氨基分子的NHS酯标记(请联系金畔生物获取)
    Cy® is a trademark of GE Healthcare.

    General properties

    Appearance: dark blue powder
    Molecular weight: 716.31
    Molecular formula: C44H46ClN3O4

     

    Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
    Quality control: NMR 1H (95%) and 13C, TLC, functional testing
    Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
    MSDS:

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    Spectral properties

     

    Excitation maximum, nm: 673
    209000  
    Emission maximum, nm: 707
    Fluorescence quantum yield: 0.2

     

     

    Product citations

    1. Jiang, X.; Bugno, J.; Hu, C.; Yang, Y.; Herold, T.; Qi, J.; Chen, P.; Gurbuxani, S.; Arnovitz, S.; Strong, J.; Ferchen, K.; Ulrich, B.; Weng, H.; Wang, Y.; Huang, H.; Li, S.; Neilly, M.B.; Larson, R.A.; Le Beau, M.M.; Bohlander, S.K.; Jin, J.; Li, Z.; Bradner, J.E.; Hong, S.; Chen, J. Eradication of acute myeloid leukemia with FLT3 ligand-targeted miR-150 nanoparticles. Cancer Research, in press. doi: 10.1158/0008-5472.CAN-15-2949
    2. Sun, Y.; Hong, S.; Ma, X.; Cheng, K.; Wang, J.; Zhang, Z.; Yang, M.; Jiang, Y.; Hong, X.; Cheng, Z. Recyclable Cu(I)/Melanin Dots for Cycloadditions, Bioconjugation and Cell Labeling. Chemical Science. doi: 10.1039/c6sc01536k
    3. Kim, K.-M.; Kim, M.K.; Paek, H.-J.; Choi, S.-J.; Oh, J.-M. Stable fluorescence conjugation of ZnO nanoparticles and their size dependent cellular uptake. Colloids and Surfaces B: Biointerfaces2016, 145, 870–877. doi: 10.1016/j.colsurfb.2016.06.006
    4. Geng, L.; Wang, Z.; Jia, X.; Han, Q.; Xiang, Z.; Li, D.; Yang, X.; Zhang, D.; Bu, X.; Wang, W.; Hu, Z.; Fang, Q. HER2 Targeting Peptides Screening and Applications in Tumor Imaging and Drug Delivery. Theranostics2016, 6(8), 1261–1273. doi:10.7150/thno.14302
    5. Yang, Q.; Li, L.; Sun, W.; Zhou, Z.; Huang, Y. Dual Stimuli-Responsive Hybrid Polymeric Nanoparticles Self-Assembled from POSS-Based Star-Like Copolymer-Drug Conjugates for Efficient Intracellular Delivery of Hydrophobic Drugs. ACS Applied Materials & Interfaces2016, 8(21), 13251–13261. doi: 10.1021/acsami.6b02403
    6. Brinkman, A.M.; Chen, G.; Wang, Y.; Hedman, C.J.; Sherer, N.M.; Havighurst, T.C.; Gong, S.; Xu, W. Aminoflavone-Loaded EGFR-Targeted Unimolecular Micelle Nanoparticles Exhibit Anti-Cancer Effects in Triple Negative Breast Cancer. Biomaterials,2016, 101, 20–31. doi: 10.1016/j.biomaterials.2016.05.041
    7. Bygd, H.C.; Bratlie, K.M. The effect of chemically modified alginates on macrophage phenotype and biomolecule transport. Journal of Biomedical Materials Research2016, 104(7), 1707–1719. doi: 10.1002/jbm.a.35700
    8. Zhao, L.; Yuan, W.; Ang, C.Y.; Qu, Q.; Dai, Y.; Gao, Y.; Luo, Z.; Wang, J.; Chen, H.; Li, M.; Li, F.; Zhao, Y. Silica-Polymer Hybrid with Self-Assembled PEG Corona Excreted Rapidly via a Hepatobiliary Route. Advanced Functional Materials2016, 26(18), 3036–3047. doi: 10.1002/adfm.201505155
    9. Al-Hilal, T.A.; Chung, S.W.; Choi, J.U.; Alam, F.; Park, J.; Kim, S.W.; Kim, S.Y.; Ahsan, F.; Kim, I.-S.; Byun, Y. Targeting prion-like protein doppel selectively suppresses tumor angiogenesis. Journal of Clinical Investigation2016, 126(4), 1251–1266. doi:10.1172/JCI83427
    10. Jiang, X.; Hu, C.; Arnovitz, S.; Bugno, J.; Yu, M.; Zuo, Z.; Chen, P.; Huang, H.; Ulrich, B.; Gurbuxani, S.; Weng, H.; Strong, J.; Wang, Y.; Li, Y.; Salat, J.; Li, S.; Elkahloun, A.G.; Yang, Y.; Neilly, M.B.; Larson, R.A.; Le Beau, M.M.; Herold, T.; Bohlander, S.K.; Liu, P.P.; Zhang, J.; Li, Z.; He, C.; Jin, J.; Hong, S.; Chen, J.;. miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia. Nature Communications2016, 7, 11452. doi: 10.1038/ncomms11452