伯乐CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

CHT ceramic hydroxyapatite (Ca5(PO4)3OH)2 support is a leading purification medium for today’s demanding downstream process industry.

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CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

Free Ceramic Hydroxyapatite reference wall charts for process purification

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CHT Ceramic Hydroxyapatite (Ca5(PO4)3OH)2 support is a leading purification medium for today’s demanding downstream process industry. This mixed-mode support offers unique selectivities and often separates biomolecules that appear homogeneous using other chromatographic methods. The diverse binding capabilities of CHT media for host cell proteins, leached protein A, antibody dimers and aggregates, nucleic acids, and viruses allow its use at any stage from initial capture to final polishing.

The robust properties of CHT Ceramic Hydroxyapatite improve efficiency, yield, and financial value through:

  • Excellent capture at elevated flow rates, enabling processing at all scales
  • Large capacity for high-titer upstream feedstocks
  • Exceptional selectivity, allowing a two-step chromatographic process

Two types of CHT Ceramic Hydroxyapatite, Type I and Type II, are available in three particle sizes, 20, 40, and 80 µm. Both types have elution characteristics similar to crystalline hydroxyapatite but also have some important differences:

  • Type I, sintered at 400°C, has a higher protein binding capacity and better capacity for acidic proteins
  • Type II, sintered at 700°C, has a lower protein binding capacity but offers better resolution of nucleic acids and certain proteins; it also has a very low affinity for albumin and is particularly well-suited for the purification of many species and classes of immunoglobulins
CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

Learn Best Practices and Guidelines for Packing CHT Media

These guidelines for handling and packing are recommended for all CHT users to ensure reproducible and high-quality results. Please download the CHT Application Guide for specific details on recommended buffers and slurry calculations.

Watch Videos | Download Application Guide


CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

Learn How CHT Media Can Maximize Purity and Recovery in Downstream Processing

This whiteboard animation video provides a brief introduction to Bio-Rad’s innovative mixed-mode chromatography media, CHT Ceramic Hydroxyapatite. The unique separation properties and selectivity of CHT Media enable you to maximize purity and recovery in a single step of downstream purification for the development of biotherapeutics.

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Supporting Documentation

How CHT Ceramic Hydroxyapatite Works Tech Note

Regulatory support files are available upon request. Bio-Rad Laboratories is an ISO 9001-registered corporation.

Related Products

  • Resin Sampler Pack

  • UNOsphere™ 阳离子交换介质

  • UNOsphere 阴离子交换介质

  • CHT Ceramic Hydroxyapatite Type I Media

  • Bio-Scale™ Mini CHT™ 40 µm 预装柱

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CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) CHT Ceramic Hydroxyapatite

1582200

10 g, CHT ceramic hydroxyapatite multimodal chromatography media, Type II, 20 μm particle size

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) CHT Ceramic Hydroxyapatite

1572000

100 g, CHT ceramic hydroxyapatite multimodal chromatography media, Type II, 20 μm particle size

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) CHT Ceramic Hydroxyapatite

157-2100

1 kg, CHT ceramic hydroxyapatite multimodal chromatography media, Type II, 20 μm particle size

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) CHT Ceramic Hydroxyapatite

157-2500

5 kg, CHT ceramic hydroxyapatite multimodal chromatography media, Type II, 20 μm particle size

本产品不再供货。欲了解更多关于更换产品的信息,请联系移动电话

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) CHT Ceramic Hydroxyapatite

1584200

10 g, CHT ceramic hydroxyapatite multimodal chromatography media, Type II, 40 μm particle size

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) CHT Ceramic Hydroxyapatite

1574000

100 g, CHT ceramic hydroxyapatite multimodal chromatography media, Type II, 40 μm particle size

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) CHT Ceramic Hydroxyapatite

157-4100

1 kg, CHT ceramic hydroxyapatite multimodal chromatography media, Type II, 40 μm particle size

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) CHT Ceramic Hydroxyapatite

157-4500

5 kg, CHT ceramic hydroxyapatite multimodal chromatography media, Type II, 40 μm particle size

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) CHT Ceramic Hydroxyapatite

1588200

10 g, CHT ceramic hydroxyapatite multimodal chromatography media, Type II, 80 μm particle size

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) CHT Ceramic Hydroxyapatite

1578000

100 g, CHT ceramic hydroxyapatite multimodal chromatography media, Type II, 80 μm particle size

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) CHT Ceramic Hydroxyapatite

157-8100

1 kg, CHT ceramic hydroxyapatite multimodal chromatography media, Type II, 80 μm particle size

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) CHT Ceramic Hydroxyapatite

157-8500

5 kg, CHT ceramic hydroxyapatite multimodal chromatography media, Type II, 80 μm particle size

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) Foresight™ CHT™ Type II Plates

7324718

2 x 96-well plates, 20 μl, filter plate prepacked with CHT Ceramic Hydroxyapatite Type II Multimodal Chromatography Media, 40 μm particle size

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) Foresight CHT Type II RoboColumn Unit

7324825

1 row of 8 columns, 200 μl, RoboColumn unit prepacked with CHT Ceramic Hydroxyapatite Type II Multimodal Chromatography Media, 40 μm particle size

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) Foresight™ CHT™ Type II RoboColumn Unit

7324826

1 row of 8 columns, 600 μl, RoboColumn unit prepacked with CHT Ceramic Hydroxyapatite Type II Multimodal Chromatography Media, 40 μm particle size

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) Foresight™ CHT™ Type II Column

7324736

Pkg of 1, 1 ml, column prepacked with CHT Ceramic Hydroxyapatite Type II Multimodal Chromatography Media, 40 μm particle size

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) Foresight™ CHT™ Type II Column

7324756

Pkg of 1, 5 ml, column prepacked with CHT Ceramic Hydroxyapatite Type II Multimodal Chromatography Media, 40 μm particle size

试剂&试剂盒

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) Media Sampler Pack

1580100

Includes 25 ml each of UNOsphere™ Q and UNOsphere S, Macro-Prep® DEAE, Macro-Prep High Q, and Macro-Prep High S; 5 ml of UNOsphere SUPrA™; 10 g each of CHT™ Ceramic Hydroxyapatite Types I and II, 40 μm; and 10 g of CFT™ Ceramic Fluoroapatite Type II, 40 μm

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) Bio-Scale Mini CHT Type II Cartridges

7324334

Pkg of 5, 5 ml, prepacked, CHT ceramic hydroxyapatite multimodal chromatography media cartridge, Type II

The following replacement is recommended:

  • EconoFit CHT Type II, 40 µm Columns, 5 x 5 ml ( 12009258 )
本产品不提供在线销售。欲了解更多信息,请联系客户服务。

CHT Ceramic Hydroxyapatite Type II Media | Bio-Rad Laboratories

(停产) Bio-Scale Mini CHT Type II Cartridge

7324332

Pkg of 1, 5 ml, prepacked, CHT ceramic hydroxyapatite multimodal chromatography media cartridge, Type II

The following replacement is recommended:

  • EconoFit CHT Type II, 40 µm Column, 1 x 5 ml ( 12009257 )
本产品不提供在线销售。欲了解更多信息,请联系客户服务。

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