Mouse anti-SERPINC1 Monoclonal Antibody(435CT4.7.4)描述别名宿主特异性反应种属应用分子量类型克隆号同种型储存/保存方法存储溶液研究领域背景说明细胞定位UniProt参考文献
| 概述 | |
| 描述 |
Mouse Monoclonal Antibody (Mab)
|
| 别名 |
SERPINC1抗体;Antithrombin-III; ATIII; Serpin C1; SERPINC1; AT3
|
| 宿主 |
Mouse
|
| 特异性 |
This SERPINC1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 364-393 amino acids from human SERPINC1.
|
| 反应种属 |
Human, Rat
|
| 应用 |
WB~~1:100~500
|
| 分子量 |
Predicted molecular weight: 53kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 性能 | |
| 类型 |
Monoclonal Antibody
|
| 克隆号 |
435CT4.7.4
|
| 同种型 |
IgG1
|
| 储存/保存方法 |
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
|
| 存储溶液 |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
|
| 研究领域 |
Cardiovascular;Cell Biology
|
| 靶标 | |
| 背景说明 |
Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.
|
| 细胞定位 |
Secreted, extracellular space.
|
| UniProt |
P01008
|
| 参考文献 | |
| 参考文献 |
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Zhang, G.S., et al. Blood Coagul. Fibrinolysis 21(6):588-591(2010) Bunkenborg, J., et al. Proteomics 4(2):454-465(2004) Picard, V., et al. Biochemistry 34(26):8433-8440(1995) |
实验结果图
SERPINC1 Antibody (Cat. #JP100232) western blot analysis in rat liver tissue lysates (35μg/lane).This demonstrates the SERPINC1 antibody detected the SERPINC1 protein (arrow).