Rabbit anti-ZNF238 Polyclonal Antibody(C-Term)描述别名宿主特异性反应种属预测反应种属应用分子量类型同种型储存/保存方法研究领域背景说明细胞定位UniProt参考文献
概述 | |
描述 |
Purified Rabbit Polyclonal Antibody (Pab)
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别名 |
ZNF238抗体;Zinc finger and BTB domain-containing protein 18; 58 kDa repressor protein; Transcriptional repressor RP58; Translin-associated zinc finger protein 1; TAZ-1; Zinc finger protein 238; Zinc finger protein C2H2-171; ZBTB18; RP58; TAZ1; ZNF238
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宿主 |
Rabbit
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特异性 |
This ZNF238 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 318-331 amino acids from human ZNF238.
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反应种属 |
Mouse
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预测反应种属 |
M, R
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应用 |
WB~~1:2000
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分子量 |
Predicted molecular weight: 58kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
性能 | |
类型 |
Polyclonal Antibody
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同种型 |
Rabbit Ig
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储存/保存方法 |
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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研究领域 |
Others
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靶标 | |
背景说明 |
Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5′- [AC]ACATCTG[GT][AC]-3′ which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus.
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细胞定位 |
Nucleus. Note=Associates with condensed chromatin
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UniProt |
Q99592
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参考文献 | |
参考文献 |
Becker K.G.,et al.Hum. Mol. Genet. 4:685-691(1995).
Aoki K.,et al.J. Biol. Chem. 273:26698-26704(1998). Meng G.,et al.Gene 242:59-64(2000). Ota T.,et al.Nat. Genet. 36:40-45(2004). Gregory S.G.,et al.Nature 441:315-321(2006). |
实验结果图
Anti-ZNF238 Antibody (C-Term) at 1:2000 dilution + mouse brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 58 kDa Blocking/Dilution buffer: 5% NFDM/TBST.