The cysteine-rich C-terminal domain of AGRP, corresponding to AGRP(87-132), exhibits receptor binding affinity and antagonism equivalent to that of the full-length protein.

Ac – Cys – Val – Arg – Leu – His – Glu – Ser – Cys – Leu – Gly – Gln – Gln – Val – Pro – Cys – Cys – Asp – Pro – Cys – Ala – Thr – Cys – Tyr – Cys – Arg – Phe – Phe – Asn – Ala – Phe – Cys – Tyr – Cys – Arg – Lys – Leu – Gly – Thr – Ala – Met – Asn – Pro

≥ 95%

-20°C

Ac – CVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCRKLGTAMNPCSRT

Ref: Yang, Y. et al. Mol. Endocrinol. 13, 148 (1999); Wilczynski, A. et al. J. Med. Chem. 47, 5662 (2004); Wilczynski, A. et al. J. Med. Chem. 47, 2194 (2004); Millhauser, G. et al. Ann. N. Y. Acad. Sci. 994, 27 (2003).