Mouse anti-FAM120A Monoclonal Antibody(1501CT803.19.85.5)描述别名宿主特异性反应种属应用分子量类型克隆号同种型储存/保存方法研究领域背景说明细胞定位UniProt参考文献
| 概述 | |
| 描述 |
Purified Mouse Monoclonal Antibody (Mab)
|
| 别名 |
FAM120A抗体;Constitutive coactivator of PPAR-gamma-like protein 1; Oxidative stress-associated Src activator; Protein FAM120A; FAM120A; C9orf10; KIAA0183; OSSA
|
| 宿主 |
Mouse
|
| 特异性 |
This FAM120A antibody is generated from a mouse immunized with a recombinant protein of human FAM120A.
|
| 反应种属 |
Human
|
| 应用 |
IF~~1:25
IHC-P~~1:25 WB~~1:4000 |
| 分子量 |
Predicted molecular weight: 122kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 性能 | |
| 类型 |
Monoclonal Antibody
|
| 克隆号 |
1501CT803.19.85.5
|
| 同种型 |
IgG1,k
|
| 储存/保存方法 |
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
|
| 研究领域 |
Cell Biology;Signal Transduction
|
| 靶标 | |
| 背景说明 |
May participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous- type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
|
| 细胞定位 |
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Translocates to plasma membrane upon ultraviolet exposure
|
| UniProt |
Q9NZB2
|
| 参考文献 | |
| 参考文献 |
Brahmbhatt S.B.,et al.Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases.
Humphray S.J.,et al.Nature 429:369-374(2004). Nagase T.,et al.DNA Res. 3:17-24(1996). Ohara O.,et al.Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases. Holden S.,et al.Gene 318:149-161(2003). |
实验结果图
All lanes : Anti-FAM120A Antibody at 1:4000 dilution Lane 1: MCF-7 whole cell lysates Lane 2: U-2OS whole cell lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 122 kDa Blocking/Dilution buffer: 5% NFDM/TBST.