BAY-4931CAS号： 423150-91-8分子式： C22H16ClN3O4分子量： 421.83描述纯度储存/保存方法可溶性/溶解性靶点In vitro(体外研究)
| 产品描述 | |
| 描述 |
BAY-4931 is a potent, covalent and selective PPARγ inverse-agonist with an IC 50 of 0.17 nM .
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
DMSO:112.5 mg/mL (266.7 mM)
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| 生物活性 | |
| 靶点 |
UM-UC-9(cell):3.4 nM, mouse PPARγ:0.14 nM, PPARγ(RT112-FABP4-NLucP cellular):0.17 nM, hPPARγ:0.40 nM
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| In vitro(体外研究) |
Fractionation of culture extracts using RP-HPLC and LC-MS showed that samples containing Questin was toxic to the human A549 lung cell line.[1]
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