NKH 477 hydrochloride

NKH 477 hydrochlorideCAS号: 138605-00-2分子式: C27H43NO8•HCl分子量: 546.1描述应用纯度储存/保存方法形态别名外观可溶性/溶解性

产品描述
描述

NKH 477 is a water-soluble analog of forskolin ; potent activator of A cyclase (adenylyl cyclase); with some selectivity for cardiac A cyclase V (type V adenylyl cyclase). Stimulates bronchodilation (EC50 = 32.6 nM) and is an orally active potent positive chronotrope and hypotensive .

应用
A potent activator of adenylyl cyclase
纯度
≥95%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
形态
Solid
基本信息
别名
NKH 477
外观
white to beige solid
可溶性/溶解性
Soluble in water (40 mM), ethanol ( ~2.5 mg/ml), DMSO (~20 mg/ml), DMF (~20 mg/ml), and 1:1 solution of DMSO:PBS (pH 7.2) (~0.5 mg/ml).

分子结构图

NKH 477 hydrochloride