This is a reverse transcriptase (RT) epitope (Pol residues 476-484). Within HIV-1 RT the peptide appears to be the dominant HLA A*0201-restricted epitope. Was used to investigate possible mechanisms behind HIV-1 escape from CTL. IV9 is the actual epito

H – Ile – Leu – Lys – Glu – Pro – Val – His – Gly – Val – OH

-20°C

ILKEPVHGV

Ref: Sewell, A. et al. The Journal of Immunology 162, 7075 (1999); Jamieson, B. et al. The Journal of Immunology 171, 5372 (2003); Ref: Brander, C. et al. J. Clin. Invest 101, 2559 (1998); Goulder,P. et al. J. Exp. Med 185, 1423 (1997)