SCIO 469 hydrochlorideCAS号： 309915-12-6分子式： C27H30ClFN4O3•HCl分子量： 549.46描述应用储存/保存方法形态别名沸点光学活性IC50可溶性/溶解性MDLPubChem CID靶点
| 产品描述 | |
| 描述 |
SCIO 469 hydrochloride has shown to be a selective, ATP-competitive p38 inhibitor. Studies suggest that this compound has a 10-fold selectivity for p38α over p38β and 2000-fold selectivity for p38α over 20 other kinases. |
| 应用 |
A selective, ATP-competitive p38 inhibitor
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 形态 |
Solid
|
| 基本信息 | |
| 别名 |
6-Chloro-5-[[(2R,5S)-4-[(4-fluoroph enyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]- N,N,1-trimethyl-α-oxo-1H-Indole-3-acetamide hydrochloride
|
| 沸点 |
677.3° C at 760 mmHg (Predicted)
|
| 光学活性 |
α20/D +22.9°, c = 1.04 in methanol
|
| IC50 |
p38α: IC50 = 9 nM
|
| 可溶性/溶解性 |
Soluble in water (10 mM), and DMSO (100 mM).
|
| MDL |
MFCD18384956
|
| PubChem CID |
16035045
|
| 生物活性 | |
| 靶点 |
p38（IC50 9nM）
|
分子结构图
