IEM 1460

IEM 1460CAS号: 121034-89-7分子式: C19H37N2Br • HBr分子量: 454.3描述纯度储存/保存方法参考文献

产品描述
描述
IEM 1460 is an adamantine derivative that blocks both AMPA- and NMDA-type glutamate receptor (GluR) channels (IC50 = 10 μM-0.1 mM).1 It is selective for Ca2+-permeable GluR channels, which lack the GluR2 R subunit, and has been used to identify Ca2+-permeable glutamate receptors in the brain.1
纯度
≥98%
储存/保存方法
Store at 22℃
参考文献
参考文献
1.Schlesinger, F.,Tammena, D.,Krampfl, K., et al. Two mechanisms of action of the adamantane derivative IEM-1460 at human AMPA-type glutamate receptors. British Journal of Pharmacology 145(5), 656-663 (2005).

分子结构图

IEM 1460