ETP 45658 is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively). Also inhibits DNA-PK and mTOR (IC50 values are 70.6 and 152 nM respectively).

98%

Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

DMSO:60 mg/ml (192.72 mM)

mTOR:152.0 nM (IC50), PI3Kγ:717.3 nM (IC50), PI3Kβ:129.0 nM (IC50), DNA-PK:70.6 nM (IC50), PI3Kα:22.0 nM (IC50), PI3Kδ:39.8 nM (IC50)