CE-224535CAS号： 724424-43-5分子式： C22H29ClN4O6分子量： 480.94描述纯度储存/保存方法别名可溶性/溶解性靶点In vitro(体外研究)In vivo(体内研究)
| 产品描述 | |
| 描述 |
CE-224535 is a selective P2X7 receptor antagonist.
|
| 纯度 |
98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 别名 |
PF-04905428
|
| 可溶性/溶解性 |
DMSO : 100 mg/mL (207.93 mM)
|
| 生物活性 | |
| 靶点 |
P2X7 receptor
|
| In vitro(体外研究) |
CE-224535 is developed as a disease-modifying antirheumatic drugs (DMARD) and is a selective antagonist of the human P2X7 receptor. CE-224535 can reduce leukocyte secretion of IL-1 and IL-18, thereby providing a novel therapeutic approach for treatment of rheumatoid arthritis (RA).
|
| In vivo(体内研究) |
CE-224535 is developed as a disease-modifying antirheumatic drugs (DMARD) and is a selective antagonist of the human P2X7 receptor. CE-224535 can reduce leukocyte secretion of IL-1 and IL-18, thereby providing a novel therapeutic approach for treatment of rheumatoid arthritis (RA).
|
分子结构图
