Rabbit anti-Phospho-mTOR(Ser2448) Polyclonal Antibody别名宿主反应种属应用分子量免疫原形式纯化方法同种型储存/保存方法存储溶液修饰背景说明UniProt
| 概述 | |
| 别名 |
MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic tar
|
| 宿主 |
Rabbit
|
| 反应种属 |
Human, Mouse, Pig
|
| 应用 |
WB: 1/500-1/1000, IHC: 1/50-1/100
|
| 分子量 |
Detects a band of approximately 289 kD(Predicted molecular weight: 289 kD)
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 免疫原 |
A synthesized peptide derived from human Phospho-mTOR (S2448)
|
| 性能 | |
| 形式 |
Polyclonal Antibody
|
| 纯化方法 |
Affinity Chromatography
|
| 同种型 |
IgG
|
| 储存/保存方法 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
|
| 存储溶液 |
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
|
| 修饰 |
Phosphorylated
|
| 靶标 | |
| 背景说明 |
An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
|
| UniProt |
P42345
|
实验结果图
Western blot analysis of Phospho-mTOR (S2448) in HEK293 lysates using Phospho-mTOR (Ser2448) antibody.
Immunohistochemistry analysis of paraffin-embedded human breast cancer using Phospho-mTOR (S2448) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.