TP0427736

TP0427736CAS号: 864374-00-5分子式: C14H10N4S2分子量: 298.39描述纯度储存/保存方法别名外观可溶性/溶解性

产品描述
描述
TP0427736 is a potent inhibitor of ALK5 kinase activity with an IC50 of 2.72 nM and this effect is 300-fold higher than the inhibitory effect on ALK3 (IC50 = 836 nM for ALK3). It also inhibits Smad2/3 phosphorylation in A549 cells induced by TGF-β1 with an IC50 value of 8.68 nM.
纯度
>98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
别名
TP-0427736
外观
浅黄色固体
可溶性/溶解性
DMSO :≥50mg/mL

实验结果图

TP0427736