GSK 264220ACAS号： 685506-42-7分子式： C17H21N3O4S分子量： 363.43描述储存/保存方法形态别名密度熔点折射率IC50PK值可溶性/溶解性MDLPubChem CID
| 产品描述 | |
| 描述 |
An endothelial lipase and a lipoprotein lipase inhibitor (IC50 values are 0.13 and 0.10 μM respectively).
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| 储存/保存方法 |
Store at 4° C
|
| 形态 |
Solid
|
| 基本信息 | |
| 别名 |
N-[2-Methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N’-phenylurea
|
| 密度 |
~1.38 g/cm3 (Predicted)
|
| 熔点 |
181-183° C
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| 折射率 |
n20D ~1.63 (Predicted)
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| IC50 |
Endothelial lipase: IC50 = 0.016 µM; Lipoprotein lipase: IC50 = 0.10 µM (rat); Endothelial lipase: IC50 = 0.13 µM (human)
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| PK值 |
pKa: 13.63 (Predicted), pKb: 0.29 (Predicted)
|
| 可溶性/溶解性 |
Soluble in DMSO (100 mM), ethanol (10 mM), DMF (30 mg/ml), and 1:3 solution of DMSO:PBS (pH 7.2) (0.25 mg/ml).
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| MDL |
MFCD02679009
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| PubChem CID |
2810413
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