BRL44408马来酸盐CAS号： 118290-27-0分子式： C27H38N6O2分子量： 478.63描述应用纯度储存/保存方法形态密度熔点沸点折射率PK值Ki 数据可溶性/溶解性PubChem CID
| 产品描述 | |
| 描述 |
AF-DX 384 is a potent mAChR M2/mAChR M4 selective antagonist (pKi values are 8.22, 8.00, 7.51, 7.18 and 6.27 at human mAChR M2/, mAChR M4, mAChR M1, mAChR M3 and mAChR M5 receptors, respectively).
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| 应用 |
A potent mAChR M2/mAChR M4 selective antagonist
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| 纯度 |
≥98%
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| 储存/保存方法 |
Store at room temperature
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| 形态 |
Solid
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| 基本信息 | |
| 密度 |
1.15 g/cm3 (Predicted)
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| 熔点 |
303.86° C (Predicted)
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| 沸点 |
618.39° C at 760 mmHg (Predicted)
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| 折射率 |
n20D 1.57 (Predicted)
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| PK值 |
pKa: 11.55 (Predicted), pKb: 9.8 (Predicted)
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| Ki 数据 |
mAChR M2: Ki= 1 nM (human); mAChR M4: Ki= 2 nM (human); mAChR M1: Ki= 12.4 nM (human); mAChR M5: Ki= 501.19 nM (human)
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| 可溶性/溶解性 |
Soluble in ethanol (10 mM), and DMSO (50 mM).
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| PubChem CID |
119357
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