JX-401CAS号： 349087-34-9分子式： C21H25NO2S分子量： 355.49描述应用纯度储存/保存方法形态别名外观密度熔点沸点折射率IC50可溶性/溶解性MDLPubChem CID靶点
| 产品描述 | |
| 描述 |
JX-401 is a potent non-cytotoxic cell membrane permeable p38α inhibitor that acts by reversibly binding MAPK p38α. Yet it is non functional against p38γ. |
| 应用 |
A potent non-cytotoxic cell membrane permeable p38α inhibitor
|
| 纯度 |
98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 形态 |
Solid
|
| 基本信息 | |
| 别名 |
1-[2-Methoxy-4-(methylthio)benzoyl]-4-benzylpiperidine
|
| 外观 |
off-white solid
|
| 密度 |
~1.2 g/cm3 (Predicted)
|
| 熔点 |
196.00° C (Predicted)
|
| 沸点 |
~537.3° C at 760 mmHg (Predicted)
|
| 折射率 |
n20D 1.61 (lit.)
|
| IC50 |
p38α: IC50 = 32 nM; p38γ: IC50 = 10 µM
|
| 可溶性/溶解性 |
Soluble in DMSO (20 mg/mL), and ethanol (10 mg/mL).
|
| MDL |
MFCD02038777
|
| PubChem CID |
1126109
|
| 生物活性 | |
| 靶点 |
p38α
|
分子结构图
