AF64394CAS号： 1637300-25-4分子式： C21H20ClN5O分子量： 393.87描述纯度储存/保存方法可溶性/溶解性靶点In vitro(体外研究)
| 产品描述 | |
| 描述 |
AF64394 is a GPR3 inverse agonist, with a pIC50 of 7.3.
|
| 纯度 |
98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 可溶性/溶解性 |
DMSO : ≥ 125 mg/mL (317.36 mM)
|
| 生物活性 | |
| 靶点 |
GPR3
|
| In vitro(体外研究) |
AF64394 is a GPR3 inverse agonist, with a pIC50 of 7.3. AF34394 and related compounds are only of modest potency and are relatively lipophilic (e.g., AF34394 clogP=5.2, LLE=2.1, and 14b clog P=3.1 and LLE=3.2) the series shows promising SAR and represents an excellent start point for further optimization.
|
分子结构图
