BMS 193885CAS号： 186185-03-5分子式： C33H42N4O6 C3H6O3分子量： 680.79描述应用纯度储存/保存方法形态折射率IC50Ki 数据可溶性/溶解性MDLPubChem CID
| 产品描述 | |
| 描述 |
BMS 193885 is a potent, competitive NPY1-R antagonist (Ki = 3.3 nM, IC50 = 5.9 nM) that displays > 47, > 100, > 160, > 160 and > 160-fold selectivity over σ1, α1, NPY2-R, NPY4-R and NPY5-R receptors respectively. Reduces food intake and body weight via central NPY1-R inhibition and is a brain penetrant.
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| 应用 |
A competitive NPY1-R antagonist
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| 纯度 |
>98%
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| 储存/保存方法 |
Desiccate at 4° C
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| 形态 |
Solid
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| 基本信息 | |
| 折射率 |
n20D ~1.57 (Predicted)
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| IC50 |
NPY1-R: IC50 = 5.9 nM
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| Ki 数据 |
NPY1-R: Ki= 3.3 nM
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| 可溶性/溶解性 |
Soluble in water (20 mM), and DMSO (100 mM).
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| MDL |
MFCD16618378
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| PubChem CID |
56972234
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