This tumor antigenic peptide presented by HLA-A2 antigen to CTLs, is a tyrosinase fragment. Tyrosinase is a membrane-bound protein involved in the melanin synthesis pathway that is expressed by virtually all primary melanoma lesions and by most of metasta

H – Tyr – Met – Asp – Gly – Thr – Met – Ser – Gln – Val – OH

≥ 95%

-20°C

YMDGTMSQV

Chapiro, J. et al. J. Immunol. 176, 1053 (2006); Paczesny, S. et al. JEM 199, 1503 (2004); Lee, P. et al J. Clin. Oncol. 19, 3836 (2001).