ML359CAS号： 1069858-99-6分子式： C19H18N4O3分子量： 350.37描述纯度储存/保存方法可溶性/溶解性靶点In vitro(体外研究)
| 产品描述 | |
| 描述 |
ML359 is a protein disulfide isomerase inhibitor.
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
DMSO:84 mg/mL (200.99 mM)
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| 生物活性 | |
| 靶点 |
protein disulfide isomerase:250 nM (IC50)
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| In vitro(体外研究) |
ML359 shown to be a specific inhibitor of PDI.?ML359 shows no cytotoxicity in three human cell lines, and some activity in inhibiting platelet aggregation in vitro.?ML359 will provide more understanding of the mechanisms of PDI in platelet functions.?It also could lead to the development of a new class of antithrombotics that could establish PDI as suitable drug target.
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