JNJ-63576253

JNJ-63576253CAS号: 2110428-64-1分子式: C23H22ClF3N6O2S分子量: 538.97描述纯度储存/保存方法可溶性/溶解性靶点In vitro(体外研究)

产品描述
描述
JNJ-63576253 is a Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC).
纯度
98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
可溶性/溶解性
DMSO:200mg/mL (371.08 mM),H2O:insoluble
生物活性
靶点
Androgen Receptor:37nM
In vitro(体外研究)
JNJ-63576253 inhibits the growth of VCaP cells,with an IC50 of 265nM[1].