CCX354CAS号: 1010073-75-2分子式: C22H22ClN7O2分子量: 451.91描述纯度储存/保存方法In vitro(体外研究)In vivo(体内研究)
产品描述 | |
描述 |
CCX354 is a potent small molecule CCR1 antagonist with anti-inflammatory activity for the treatment of rheumatoid arthritis.
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纯度 |
98%
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储存/保存方法 |
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
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生物活性 | |
In vitro(体外研究) |
CCX354 displays potent activities in the chemotaxis assay (IC50<100 nM).[1]
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In vivo(体内研究) |
CCX354 has in vivo anti-inflammatory activity. It also has superior pharmacokinetic properties.[1]
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