ML-354

ML-354CAS号: 89159-60-4分子式: C16H14N2O3分子量: 282.3描述纯度储存/保存方法别名参考文献

产品描述
描述
ML-354 is an indole-based, proteinase-activated receptor 4 (PAR4) antagonist (IC50 = 140 nM) that exhibits 71-fold selectivity for PAR4 over PAR1 (IC50 = 10 μM) in isolated human platelets.1
纯度
≥95%
储存/保存方法
Store at -20℃
基本信息
别名
VU0099704;
参考文献
参考文献
1.Wen, W.,Young, S.E.,Duvernay, M.T., et al. Substituted indoles as selective protease activated receptor 4 (PAR-4) antagonists: Discovery and SAR of ML354. Bioorganic & Medicinal Chemistry Letters 24, 4708-4713 (2014).

分子结构图

ML-354