CGS 35066CAS号： 261619-50-5分子式： C16H16NO6P分子量： 349.28描述应用纯度储存/保存方法形态别名密度熔点沸点折射率PK值可溶性/溶解性MDLPubChem CID
| 产品描述 | |
| 描述 |
CGS 35066 is a a potent endothelin-converting enzyme (ECE) inhibitor. When compared to neutral endopeptidase 24.11, it displays > 100-fold selectivity (IC50 values are 22 and 2300 nM respectively). Another interesting property of CGS 35066 is that it blocks the hypertensive effects induced by big ET-1 in vitro and is able to reduce the magnitude of cerebral vasospasm following subarachnoid hemorrhage (SAH).
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| 应用 |
A potent endothelin-converting enzyme (ECE) inhibitor
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| 纯度 |
>98%
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| 储存/保存方法 |
Desiccate at room temperature
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| 形态 |
Solid
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| 基本信息 | |
| 别名 |
α-[(S)-(Phosphonomethyl)amino]-3-dibenzofuranpropanoic acid
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| 密度 |
~1.5 g/cm3 (Predicted)
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| 熔点 |
304.03° C (Predicted)
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| 沸点 |
~638.89° C at 760 mmHg (Predicted)
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| 折射率 |
n20D 1.70 (Predicted)
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| PK值 |
pKa: 0.79, pKb: 10.58
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| 可溶性/溶解性 |
Soluble in 1eq. NaOH to 100 mM
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| MDL |
MFCD09971085
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| PubChem CID |
9863167
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