AEG 3482CAS号： 63735-71-7分子式： C10H8N4O2S2分子量： 280.3描述纯度储存/保存方法外观可溶性/溶解性PubChem CID
| 产品描述 | |
| 描述 |
AEG 3482 is a cell-permeable imidazothiadiazole compound that activates cellular transcription factor HSF1 by binding to HSP90 and disrupting its association with HSF1. AEG 3482 has been shown to induce HSF1-dependent expression of HSP70 and HSP25 and effectively block NRAGE- and p75NTR-mediated JNK activation and apoptosis in PC12 cells in a dose-dependent manner (>90% inhibition at 40 μM). |
| 纯度 |
98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 外观 |
aint yellow to dark yellow powder
|
| 可溶性/溶解性 |
DMSO :≥15 mg/mL
|
| PubChem CID |
698112
|
分子结构图
