ML347CAS号： 1062368-49-3分子式： C22 H16 N4 O分子量： 352.39描述纯度储存/保存方法别名外观可溶性/溶解性靶点In vitro(体外研究)
| 产品描述 | |
| 描述 |
ML347 is a selective BMP receptor inhibitor with IC50 of 32 nM for ALK2, >300-fold selectivity over ALK3. Also inhibits ALK1 activity with IC50 of 46 nM
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| 纯度 |
>98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 别名 |
ML 347; ML-347; LDN-193719; LDN193719; LDN 193719
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| 外观 |
Powder
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| 可溶性/溶解性 |
DMSO 10 mg/mL (28.37 mM)
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| 生物活性 | |
| 靶点 |
ALK2 ,ALK1
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| In vitro(体外研究) |
ML347 also shows potency in BMP-responsive C2C12BRA cells with IC50 of 15 nM, and designated an MLPCN probe. ML347 displays high plasma protein binding in human, rat and mouse plasma.
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分子结构图
