CGP-53353CAS号： 145915-60-2分子式： C20H13F2N3O2分子量： 365.33描述应用纯度储存/保存方法别名外观密度熔点沸点折射率PK值可溶性/溶解性MDLPubChem CID
| 产品描述 | |
| 描述 |
CGP-53353 (DAPH-7) is an potent PKC inhibitor with IC50s of 0.41 μM and 3.8 μM for PKCβII and PKCβI, respectively. CGP-53353 can inhibit glucose-induced cell proliferation and DNA synthesis in AoSMC and A10 cells. CGP-53353 can be used for researching atherosclerosis of diabetic patients.
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| 应用 |
A highly selective PKCβII inhibitor
|
| 纯度 |
≥98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 别名 |
DAPH-7
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| 外观 |
orange solid
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| 密度 |
1.47 g/cm3
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| 熔点 |
273.71° C
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| 沸点 |
630.82° C (Predicted)
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| 折射率 |
n20D 1.70
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| PK值 |
pKa: 8.95, pKb: 0.53
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| 可溶性/溶解性 |
DMSO : ≥ 50 mg/mL (136.86 mM)
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| MDL |
MFCD00938569
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| PubChem CID |
6711154
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分子结构图
