ABT-333

ABT-333CAS号: 1132935-63-7分子式: C26H27N3O5S分子量: 493.57描述纯度储存/保存方法别名可溶性/溶解性参考文献

产品描述
描述

ABT-333 is a nonnucleoside NS5B polymerase inhibitor for the treatment of HCV infection. An interferon-free combination of the protease inhibitor ABT-450 with ritonavir (ABT-450/r), the nonnucleoside polymerase inhibitor ABT-333, and ribavirin showed efficacy against the hepatitis C virus (HCV) in a pilot study involving patients with HCV genotype 1 infection. ABT-333 is currently under clinical trials for the treatment of Hepatitis C.

纯度
>98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
别名
Dasabuvir
可溶性/溶解性
DMSO ≥46 mg/mL
参考文献
参考文献
Phase 2b trial of interferon-free therapy for hepatitis C virus genotype 1.
Kowdley KV,et al. N Engl J Med. 2014 Jan 16;370(3):222-32. PMID: 24428468.
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分子结构图

ABT-333