Mouse anti-MMP9 Monoclonal Antibody(331CT17.4.4)描述别名宿主特异性反应种属应用分子量类型克隆号同种型储存/保存方法存储溶液研究领域背景说明细胞定位UniProt参考文献
| 概述 | |
| 描述 |
Mouse Monoclonal Antibody (Mab)
|
| 别名 |
MMP9抗体;Matrix metalloproteinase-9; MMP-9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELB; 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9; MMP9; CLG4B
|
| 宿主 |
Mouse
|
| 特异性 |
Purified His-tagged MMP9 protein(Fragment) was used to produced this monoclonal antibody.
|
| 反应种属 |
Human
|
| 应用 |
WB~~1:100~250
|
| 分子量 |
Predicted molecular weight: 78kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 性能 | |
| 类型 |
Monoclonal Antibody
|
| 克隆号 |
331CT17.4.4
|
| 同种型 |
IgM
|
| 储存/保存方法 |
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
|
| 存储溶液 |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
|
| 研究领域 |
Cancer;Cardiovascular;Cell Biology;Signal Transduction
|
| 靶标 | |
| 背景说明 |
May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
|
| 细胞定位 |
Secreted, extracellular space, extracellular matrix
|
| UniProt |
P14780
|
| 参考文献 | |
| 参考文献 |
Lacchini, R., et al. Clin. Chim. Acta 411 (23-24), 1940-1944 (2010) :
Chambers, M.A., et al. Biochem. Biophys. Res. Commun. 400(3):403-408(2010) Beeghly-Fadiel, A., et al. Breast Cancer Res. Treat. (2010) In press : Szczudlik, P., et al. Neurol. Neurochir. Pol. 44(4):350-357(2010) Mossbock, G., et al. Mol. Vis. 16, 1764-1770 (2010) : |
实验结果图
MMP9 Antibody (Cat. #JP100167) western blot analysis in CEM cell line lysates (35μg/lane).This demonstrates the MMP9 antibody detected the MMP9 protein (arrow).