L-690,330CAS号： 142523-38-4分子式： C8H12O8P2分子量： 298.12描述应用纯度储存/保存方法形态别名密度熔点沸点折射率IC50PK值Ki 数据可溶性/溶解性MDLPubChem CID
| 产品描述 | |
| 描述 |
L-690,330 is a bisphosphonate inhibitor of IMPA (inositol monophosphatase). This compound is described to dose-dependently increase brain inositol(I)phosphate levels in vivo during cholinergic stimulation. The effects of L-690,330 in peripheral tissues are described to mimic those of lithium both qualitatively and quantitatively. |
| 应用 |
A potent inositol monophosphatase inhibitor
|
| 纯度 |
≥96%
|
| 储存/保存方法 |
Store at room temperature
|
| 形态 |
Solid
|
| 基本信息 | |
| 别名 |
[1-(4-hydroxyphenoxy)-1-phosphonoethyl]phosphonic acid
|
| 密度 |
~1.8 g/cm3 (Predicted)
|
| 熔点 |
90.27° C (Predicted)
|
| 沸点 |
~696.9° C at 760 mmHg (Predicted)
|
| 折射率 |
n20D 1.63 (Predicted)
|
| IC50 |
IMPA1: IC50 = 330 nM (Bos taurus)
|
| PK值 |
pKa: 1.44 (Predicted)
|
| Ki 数据 |
IMPA2: Ki= 3.16 µM (human); IMPA1: Ki= 3.16 µM (human)
|
| 可溶性/溶解性 |
Soluble in water (100 mM), DMSO, and ethanol.
|
| MDL |
MFCD00673897
|
| PubChem CID |
132449
|