AZD3264CAS号： 1609281-86-8分子式： C21H23N5O4S 分子量： 441.5描述纯度储存/保存方法可溶性/溶解性靶点In vitro(体外研究)In vivo(体内研究)参考文献
| 产品描述 | |
| 描述 |
AZD3264 is a novel IKK2 inhibitor.
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| 纯度 |
99.56 %
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
体外:
DMSO 88mg/mL(199.32mM) Ethanol 2mg/mLwarming(4.53mM) Water <1mg> |
| 生物活性 | |
| 靶点 |
IKK2
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| In vitro(体外研究) |
AZD3264, by inhibiting IKK2, prevents inflammatory conditions such as asthma, chronic pulmonary obstructive disorder (COPD) and rheumatoid arthritis.
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| In vivo(体内研究) |
AZD3264 is a selective IkB-kinase IKK2 inhibitor, which is currently in preclinical development for the potential treatment of chronic pulmonary obstructive disorder (COPD) and asthma.
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| 参考文献 | |
| 参考文献 |
[1] Murugan A, et al. Org. Process Res. Dev. 2014, 18, 646−651. |
分子结构图
