(±)-SLV 319CAS号： 362519-49-1分子式： C23H20Cl2N4O2S分子量： 487.40描述应用储存/保存方法形态别名外观密度熔点沸点折射率IC50Ki 数据可溶性/溶解性MDLPubChem CID
| 产品描述 | |
| 描述 |
(±)-SLV 319 is the mixture of the CB1 receptor antagonist SLV 319 and its distomer, SLV 319 (+)-enantiomer. SLV 319 is a potent and selective CB1 receptor antagonist (Ki = 7.8 nM) over CB2 (Ki = 7,943 nM). SLV 319 is more water soluble than other known CB1 receptor ligands due to its decreased lipophilicity.
|
| 应用 |
A mixture of the CB1 antagonist SLV 319 and its distomer
|
| 储存/保存方法 |
Store at -20° C
|
| 形态 |
Solid
|
| 基本信息 | |
| 别名 |
Ibipinabant
|
| 外观 |
Crystalline
|
| 密度 |
~1.4 g/cm3 (Predicted)
|
| 熔点 |
261.63° C (Predicted)
|
| 沸点 |
~623.2° C at 760 mmHg (Predicted)
|
| 折射率 |
n20D 1.66 (Predicted)
|
| IC50 |
CB1: IC50 = 1.91 nM (human)
|
| Ki 数据 |
CB1: Ki= 25 nM (human)
|
| 可溶性/溶解性 |
Soluble in ethanol (~30 mg/ml), DMSO (~30 mg/ml), DMF (~30 mg/ml), 1: 2 solution of ethanol: PBS (pH 7.2) (~0.25 mg/ml), and water (0.25 mg/ml at 25° C).
|
| MDL |
MFCD12912330
|
| PubChem CID |
11179267
|