LY 231617 is a potent antioxidant that readily crosses the blood-brain barrier. LY 231617 significantly reduces ischemia-induced or hydrogen peroxide-induced neuronal damage and inhibits lipid peroxidation (IC₅₀ = 22 µM). Prevents nuclear translocation of activated NF-κB in hippocampal neurons.

A potent antioxidant that readily crosses the blood-brain barrier

≥95%

Store at -20° C

Solid

316.4° C at 760 mmHg (Predicted)

n²⁰_D ~1.50 (Predicted)

lipid peroxidation: IC₅₀ = 22 µM

Soluble in DMSO (100 mg/ml), and methanol (100 mg/ml).

MFCD00919199

178576