MLS-573151 CAS号： 10179-57-4分子式： C21H19N3O2S分子量： 377.5描述纯度储存/保存方法别名外观可溶性/溶解性In vitro(体外研究)
| 产品描述 | |
| 描述 |
MLS-573151 (MLS000573151) is a selective GTPase Cdc42 inhibitor with an EC50 of 2 μM. MLS-573151 is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding of GTP to Cdc42.
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| 纯度 |
≥98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 别名 |
MLS000573151
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| 外观 |
Yellow solid
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| 可溶性/溶解性 |
DMSO : 100 mg/mL (264.93 mM; Need ultrasonic)
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| 生物活性 | |
| In vitro(体外研究) |
The fluorescence intensities of phagocytosed beads or bacteria in hemocytes, taken as a measure of phagocytosis efficiency, were markedly reduced in granulocytes treated with MLS-573151 (50 μM; for 15 min) compared to that in the control group. MLS-573151 could effectively inhibit the phagocytic ability of granulocytes.
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分子结构图
