Telomerase Inhibitor IX, also called MST-312, is a synthetic compound that acts as a reversible TERT (telomerase) inhibitor, and is described to be more potent than epigallocatechin gallate . UP37 cell studies suggest that in the presence of Telomerase Inhibitor IX, cell growth slows and the cells remain in the G₀-G₁ cell cycle arrest. In addition, reports indicate that Telomerase Inhibitor IX does not inhibit Taq DNA polymerase .

A potent, reversible inhibitor of telomerase activity

≥95%

Store at -20° C

Solid

~1.6 g/cm³ (Predicted)

219-222° C

~526.7° C at 760 mmHg (Predicted)

n²⁰_D 1.8 (Predicted)

telomerase activity: IC₅₀ = 670 nM (TRAP lysate prepared from U937 cells); Taq DNA polymerase: IC₅₀ = >3 µM

Soluble in DMSO (≥20 mg/ml).