LY311727CAS号： 164083-84-5分子式： C22H27N2O5P分子量： 430.43描述应用纯度储存/保存方法形态折射率IC50可溶性/溶解性PubChem CID
| 产品描述 | |
| 描述 |
LY 311727 is a specific group II sPLA2 (phospholipase A2 (PLA2)) inhibitor which has been reported to attenuate VEGF-mediated platelet-activating factor (PAF) synthesis in HUVEC and BAEC cells.
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| 应用 |
A specific PLA2 inhibitor reported to attenuate VEGF-mediated platelet-activating factor synthesis
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| 纯度 |
≥97%
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| 储存/保存方法 |
Store at 4° C
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| 形态 |
Solid
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| 基本信息 | |
| 折射率 |
n20D 1.62 (Predicted)
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| IC50 |
sPLA2 group IIA: IC50 <1 µm; spla2 group v: ic50 <50 µm; phospholipase a2 group iia: ic50 = 23 nM (human); Phospholipase A2 group 1B: IC50 = 8 µM (Sus scrofa)
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| 可溶性/溶解性 |
Soluble in DMSO (100 mM), and 1eq. NaOH (100 mM).
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| PubChem CID |
155922
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