CB30865CAS号: 206275-15-2分子式: C26H22BrN5O2分子量: 516.39描述纯度储存/保存方法别名可溶性/溶解性靶点
产品描述 | |
描述 |
CB30865(ZM 242421) is a potent inhibitor of Nampt , an enzyme present in the NAD biosynthetic pathway. IC50 value:Target: NamptCancer cells develop dependence on Nampt due to increased energy requirements and the elevated activity of NAD consuming enzymes such as sirtuins and mono and poly(ADP-ribose) polymerases (PARPs). These findings suggest new chemical starting points for Nampt inhibitors and further implicate this enzyme as a target in cancer.
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纯度 |
98%
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储存/保存方法 |
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
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基本信息 | |
别名 |
ZM 242421
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可溶性/溶解性 |
DMSO : 33.33 mg/mL (64.54 mM; Need ultrasonic)
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生物活性 | |
靶点 |
Nampt
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分子结构图