JNJ 303CAS号： 878489-28-2分子式： C21H29ClN2O4S分子量： 440.98描述应用纯度储存/保存方法形态别名密度熔点沸点折射率IC50可溶性/溶解性MDLPubChem CID
| 产品描述 | |
| 描述 |
JNJ 303 has been shown to act as a potent IKs blocker with an IC50of ~64 nM. This compound does not display effects on other cardiac channels; IC50 values are 3.3, >10, 11.1 and 12.6 µM for INa, ICa, Ito and IKr channels respectively.
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| 应用 |
A potent IKS blocker that does not display effects on other cardiac channels
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| 纯度 |
≥98%
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| 储存/保存方法 |
Desiccate at 4° C
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| 形态 |
Solid
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| 基本信息 | |
| 别名 |
2-(4-Chlorophenoxy)-2-methyl-N-[5-[(methylsulfonyl)amino]tricyclo[3.3.1.13,7]dec-2-yl]-propanamide
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| 密度 |
~1.3 g/cm3 (Predicted)
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| 熔点 |
247.15 °C (Predicted)
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| 沸点 |
573.98 °C (Predicted)
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| 折射率 |
n20D 1.60 (Predicted)
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| IC50 |
IKs : IC50 = 64 nM; ICa : IC50 = >10 µM; Ito : IC50 = 11.1 µM; IKr : IC50 = 12.6 µM; INa : IC50 = 3.3 µM
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| 可溶性/溶解性 |
Soluble in DMSO (25 mM).
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| MDL |
MFCD18086905
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| PubChem CID |
11575823
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