Evofosfamide(TH-302)

Evofosfamide(TH-302)CAS号: 918633-87-1分子式: C9H16Br2N5O4P分子量: 449.04描述纯度储存/保存方法别名外观可溶性/溶解性

产品描述
描述
TH-302 is selective hypoxia-activated prodrug targeting hypoxic regions of solid tumors with IC50 of 19 nM, demonstrates 270-fold enhanced cytotoxicity under hypoxia versus their potency under aerobic conditions, stable to cytochrome P450 metabolism.
纯度
>98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
别名
TH 302; TH302
外观
Powder
可溶性/溶解性
DMSO 90 mg/mL (200.42 mM)

Ethanol 90 mg/mL (200.42 mM)

Water 10 mg/mL warmed (22.26 mM)

分子结构图

Evofosfamide(TH-302)