L-371,257CAS号： 162042-44-6分子式： C28H33N3O6分子量： 507.58描述储存/保存方法外观折射率IC50PK值Ki 数据可溶性/溶解性
| 产品描述 | |
| 描述 |
L-371,257 is a potent and selective oxytocin receptor inhibitor. It displays >800-fold selectivity over human arginine vasopressin receptors V1aand V2.
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 外观 |
Solid
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| 折射率 |
n20D 1.60 (Predicted)
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| IC50 |
Rattus norvegicus: IC50 = 25 nM (rat); Oxytocin receptor: IC50 = 640 nM (rat)
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| PK值 |
pKb: 0.73 (Predicted)
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| Ki 数据 |
Vasopressin V1a receptor: Ki= 3.7 nM (rat); Oxytocin receptor: Ki= 4.6 nM (rat); AVP Receptor V1a: Ki= 3.2 µM (human); Vasopressin V2 receptor: Ki= >30 µM (rat)
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| 可溶性/溶解性 |
10 mM in DMSO
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分子结构图
