BMS-202CAS号： 1675203-84-5分子式： C25H29N3O3分子量： 419.52描述纯度储存/保存方法别名外观可溶性/溶解性靶点In vitro(体外研究)
| 产品描述 | |
| 描述 |
PD-1/PD-L1 inhibitor 2 is reported to prevent the interaction of PD-L1 with PD-1 with an IC50 value of 18 nM,a useful compound immunomodulator compound. |
| 纯度 |
>98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 别名 |
PD1 inhibitor 2; PD 1 inhibitor 2; BMS202; BMS 202
|
| 外观 |
Powder
|
| 可溶性/溶解性 |
DMSO 83 mg/mL (197.84 mM)
Ethanol 83 mg/mL (197.84 mM) |
| 生物活性 | |
| 靶点 |
PD-1_PD-L1
|
| In vitro(体外研究) |
BMS-202 inhibits PD-1/PD-Ll interaction, and may augment therapeutic immune response to a number of histologically distinct tumors. Blockade of the PD-1/PD-Ll ligation using antibodies to PD-Ll has been shown to restore and augment T cell activation in many systems.
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分子结构图
