Mouse anti-CREB1 Monoclonal Antibody(1335CT115.203.189)描述别名宿主特异性反应种属应用分子量类型克隆号同种型储存/保存方法研究领域背景说明细胞定位UniProt参考文献
| 概述 | |
| 描述 |
Purified Mouse Monoclonal Antibody (Mab)
|
| 别名 |
CREB1抗体;Cyclic AMP-responsive element-binding protein 1; CREB-1; cAMP-responsive element-binding protein 1; CREB1
|
| 宿主 |
Mouse
|
| 特异性 |
This CREB1 antibody is generated from a mouse immunized with a recombinant protein from human CREB1.
|
| 反应种属 |
Human, Mouse, Rat
|
| 应用 |
WB~~1:1000
|
| 分子量 |
Predicted molecular weight: 35kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 性能 | |
| 类型 |
Monoclonal Antibody
|
| 克隆号 |
1335CT115.203.189
|
| 同种型 |
IgG1,κ
|
| 储存/保存方法 |
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
|
| 研究领域 |
Cancer;Cell Biology;Immunology;Microbiology;Neuroscience;Signal Transduction
|
| 靶标 | |
| 背景说明 |
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
|
| 细胞定位 |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00312, ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:12552083}
|
| UniProt |
P16220
|
| 参考文献 | |
| 参考文献 |
Berkowitz L.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:5258-5262(1990).
Yoshimura T.,et al.EMBO J. 9:2537-2542(1990). Waeber G.,et al.Trans. Assoc. Am. Physicians 103:28-37(1990). Hoeffler J.P.,et al.Science 242:1430-1433(1988). Short M.L.,et al.Nucleic Acids Res. 19:4290-4290(1991). |
实验结果图
Western blot analysis of lysates from A549, mouse Neuro-2a, mouse NIH/3T3, rat C6 cell line (from left to right) using CREB1 Antibody (Cat. # JP100312). JP100312 was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysates at 35μg per lane.