BSJ-03-123CAS号： 2361493-16-3分子式： C48H57N9O11分子量： 937.01描述纯度储存/保存方法可溶性/溶解性In vitro(体外研究)
| 产品描述 | |
| 描述 |
BSJ-03-123 is a potent, CDK6-selective small-molecule degrader.
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
H2O:Insoluble,DMSO:115 mg/mL (122.73 mM)
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| 生物活性 | |
| In vitro(体外研究) |
BSJ-03-123 induced rapid, dose-dependent ternary complex formation with CDK6 and CRBN, but not with CDK4 and CRBN. Ternary complex formation was prevented by blocking binding sites on CDK6 or CRBN via pretreatment with palbo or lenalidomide.
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