EUK 118

EUK 118CAS号: 186299-34-3分子式: C22H25MnN2O8分子量: 500.4描述应用储存/保存方法形态IC50可溶性/溶解性

产品描述
描述
EUK 118 is a structural analog of EUK 8 and EUK 134 with significantly reduced activity and exhibiting a catalase activity of 35 μM O2 formed/minute from 10 mM hydrogen peroxide. Superoxide-mediated reduction of an electron acceptor (i.e., SOD mimetic activity) was inhibited by EUK 118 and EUK 8. EUK 118 exhibited no protection of human dermal fibroblasts against hydrogen peroxide-induced cell death.
应用
A structural analog of EUK 8 and EUK 134
储存/保存方法
Store at -20° C
形态
Solid
基本信息
IC50
Superoxide-mediated reduction of an electron acceptor: IC50 = 2 µM
可溶性/溶解性
Soluble in water (0.2 mg/ml at 25.0° C), ethanol (~1 mg/ml), DMSO (~20 mg/ml), and PBS (pH 7.2) (~0.2 mg/ml).