Tyrphostin AG 112CAS号： 144978-82-5分子式： C13H8N4O 分子量： 236.23描述应用储存/保存方法形态别名密度熔点沸点折射率IC50PK值可溶性/溶解性MDLPubChem CID
| 产品描述 | |
| 描述 |
Tyrphostin AG 112 is an inhibitor of the epidermal growth factor receptor (EGFR).
|
| 应用 |
An EGFR inhibitor
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| 储存/保存方法 |
Store at -20° C
|
| 形态 |
Solid
|
| 基本信息 | |
| 别名 |
Tyrphostin A48; 3-Amino-2,4-dicyano-5-(4′-hydroxyphenyl)penta-2,4-dienonitrile
|
| 密度 |
1.38 g/cm3 (Predicted)
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| 熔点 |
228-229° C
|
| 沸点 |
642.03° C at 760 mmHg (Predicted)
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| 折射率 |
n20D 1.69 (Predicted)
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| IC50 |
EGFR: IC50 = 100 nM (human); EGFR: IC50 = 125 nM; Plasmodium falciparum: IC50 = 12.59 µM
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| PK值 |
pKa: 8.99 (Predicted)
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| 可溶性/溶解性 |
Soluble in DMSO (10 mg/ml), and ethanol (1 mg/ml).
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| MDL |
MFCD00236447
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| PubChem CID |
5328804
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