SB 399885 hydrochloride is an effective, brain penetrant, and orally active antagonist of SR-6. It shows 200-fold selectivity for SR-6 over other serotonin receptors (pKi: 9.11, 8.81, and 9.02 for human recombinant, native rat, and native human SR-6 receptors, respectively).

98%

Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

DMSO:55 mg/ml (123.22 mM)

SR-6 (human recombinant):9.11 (pKi), SR-6 (native rat):8.81 (pKi), SR-6 (native human):9.02 (pKi)