TAK-981CAS号： 1858276-04-6分子式： C25H28ClN5O5S2分子量： 578.10描述纯度储存/保存方法别名可溶性/溶解性靶点In vitro(体外研究)In vivo(体内研究)
| 产品描述 | |
| 描述 |
TAK-981 is a first in class and selective inhibitor of the SUMOylation enzymatic cascade, with potential immune-activating and antineoplastic activities.
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 别名 |
Subasumstat
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| 可溶性/溶解性 |
DMSO : 75 mg/mL (129.74 mM; Need ultrasonic)
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| 生物活性 | |
| 靶点 |
SUMOylation
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| In vitro(体外研究) |
TAK-981 is able to increase the production of type 1 IFN, thereby increasing type 1 IFN-mediated signaling, activating innate effector cells and enhancing the antitumor innate immune responses.
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| In vivo(体内研究) |
A single sub-cutaneous injection of TAK-981 in naive Balb/c mice at the brachial lymph nodes induces activation of DCs.
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分子结构图
