RSM-932ACAS号： 850807-63-5分子式： C46H38Cl2N4Br2分子量： 877.54描述纯度储存/保存方法可溶性/溶解性In vitro(体外研究)In vivo(体内研究)
| 产品描述 | |
| 描述 |
RSM-932A (TCD-717) is a specific ChoKα inhibitor with IC50s of 1 and 33 μM against human recombinant ChoKα and ChoKβ enzymes, respectively. RSM-932A possesses potent ex vivo antitumor activity and low toxicity.
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
DMSO:55 mg/mL (68.95 mM)
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| 生物活性 | |
| In vitro(体外研究) |
RSM-932A exhibits effective anti proliferative activity against most tumor derived cell lines tested, including those from breast, lung, colon, bladder, liver, ovary, bone, cervix, kidney, pancreas, melanoma, and brain tumors, with an IC50 of 1.3-7.1 μM at 72 hours [1]
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| In vivo(体内研究) |
RSM-932A exhibits strong in vivo anticancer activity and is not toxic at effective doses [1].
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